Publikationen in PubMed hier
57. Fischer S, Lichtenthaeler C, Stepanenko A, Heyl F, Maticzka D, Kemmerer K, Klostermann M, Backofen R, Zarnack K, Weigand JE. (2023) Heterogenous nuclear ribonucleoprotein D-like controls endothelial cell functions. Biol Chem. 405: 229-239.
56. Vögele J, Hymon D, Martins J, Ferner J, Jonker HRA, Hargrove AE, Weigand JE, Wacker A, Schwalbe H, Wöhnert J, Duchardt-Ferner E. (2023) High-resolution structure of stem-loop 4 from the 5′-UTR of SARS-CoV-2 solved by solution state NMR. Nucleic Acids Res. 51: 11318-11331.
55. Kaiser C, Vogel M, Appel B, Weigand J, Müller S, Suess B, Wachtveitl J. (2023) Magnesium Ion-Driven Folding and Conformational Switching Kinetics of Tetracycline Binding Aptamer: Implications for in vivo Riboswitch Engineering. J Mol Biol. 435: 168253.
54. Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Richter C, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Schwalbe H. (2023) The COVID19-NMR Consortium: A Public Report on the Impact of this New Global Collaboration. Angew Chem Int Ed Engl. 62: e202217171.
53. Berg H, Wirtz Martin MA, Altincekic N, Alshamleh I, Kaur Bains J, Blechar J, Ceylan B, de Jesus V, Dhamotharan K, Fuks C, Gande SL, Hargittay B, Hohmann KF, Hutchison MT, Marianne Korn S, Krishnathas R, Kutz F, Linhard V, Matzel T, Meiser N, Niesteruk A, Pyper DJ, Schulte L, Trucks S, Azzaoui K, Blommers MJJ, Gadiya Y, Karki R, Zaliani A, Gribbon P, da Silva Almeida M, Dinis Anobom C, Bula AL, Bütikofer M, Putinhon Caruso Í, Caterina Felli I, Da Poian AT, Cardoso de Amorim G, Fourkiotis NK, Gallo A, Ghosh D, Gomes-Neto F, Gorbatyuk O, Hao B, Kurauskas V, Lecoq L, Li Y, Cunha Mebus-Antunes N, Mompeán M, Cristtina Neves-Martins T, Ninot-Pedrosa M, Pinheiro AS, Pontoriero L, Pustovalova Y, Riek R, Robertson AJ, Jose Abi Saad M, Treviño MÁ, Tsika AC, Almeida FCL, Bax A, Henzler-Wildman K, Hoch JC, Jaudzems K, Laurents DV, Orts J, Pierattelli R, Spyroulias GA, Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Löhr F, Qureshi N, Richter C, Saxena K, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H. (2022) Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development. Angew Chem Int Ed Engl. 61: e202205858.
52. Mertinkus KR, Grün JT, Altincekic N, Bains JK, Ceylan B, Ferner JP, Frydman L, Fürtig B, Hengesbach M, Hohmann KF, Hymon D, Kim J, Knezic B, Novakovic M, Oxenfarth A, Peter SA, Qureshi NS, Richter C, Scherf T, Schlundt A, Schnieders R, Schwalbe H, Stirnal E, Sudakov A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Martin MAW, Wöhnert J. (2022) 1H, 13C and 15N chemical shift assignment of the stem-loops 5b + c from the 5′-UTR of SARS-CoV-2. Biomol NMR Assign. 16: 17-25.
51. Richter C, Hohmann KF, Toews S, Mathieu D, Altincekic N, Bains JK, Binas O, Ceylan B, Duchardt-Ferner E, Ferner J, Fürtig B, Grün JT, Hengesbach M, Hymon D, Jonker HRA, Knezic B, Korn SM, Landgraf T, Löhr F, Peter SA, Pyper DJ, Qureshi NS, Schlundt A, Schnieders R, Stirnal E, Sudakov A, Vögele J, Weigand JE, Wirmer-Bartoschek J, Witt K, Wöhnert J, Schwalbe H, Wacker A. (2021) 1H, 13C and 15N assignment of stem-loop SL1 from the 5′-UTR of SARS-CoV-2. Biomol NMR Assign, 15: 467-474.
50. Lichtenthaeler C, Oberstrass L, Weigand JE (2021) mRNA-Strukturen steuern die posttranskriptionelle Genregulation. Biospektrum 27: 351-354.
49. Sreeramulu S, Richter C, Berg H, Wirtz Martin MA, Ceylan B, Matzel T, Adam J, Altincekic N, Azzaoui K, Bains JK, Blommers MJJ, Ferner J, Fürtig B, Göbel M, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Martins J, Mertinkus KR, Niesteruk A, Peter SA, Pyper DJ, Qureshi NS, Scheffer U, Schlundt A, Schnieders R, Stirnal E, Sudakov A, Tröster A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H (2021) Exploring the druggability of conserved RNA regulatory elements in the SARS-CoV-2 genome. Angew Chem Int Ed Engl 60: 19191-19200.
48. Altincekic N, Korn SM, Qureshi NS, Dujardin M, Ninot-Pedrosa M, Abele R, Abi Saad MJ, Alfano C, Almeida FCL, Alshamleh I, de Amorim GC, Anderson TK, Anobom CD, Anorma C, Bains JK, Bax A, Blackledge M, Blechar J, Böckmann A, Brigandat L, Bula A, Bütikofer M, Camacho-Zarco AR, Carlomagno T, Caruso IP, Ceylan B, Chaikuad A, Chu F, Cole L, Crosby MG, de Jesus V, Dhamotharan K, Felli IC, Ferner J, Fleischmann Y, Fogeron ML, Fourkiotis NK, Fuks C, Fürtig B, Gallo A, Gande SL, Gerez JA, Ghosh D, Gomes-Neto F, Gorbatyuk O, Guseva S, Hacker C, Häfner S, Hao B, Hargittay B, Henzler-Wildman K, Hoch JC, Hohmann KF, Hutchison MT, Jaudzems K, Jović K, Kaderli J, Kalniņš G, Kaņepe I, Kirchdoerfer RN, Kirkpatrick J, Knapp S, Krishnathas R, Kutz F, Zur Lage S, Lambertz R, Lang A, Laurents D, Lecoq L, Linhard V, Löhr F, Malki A, Bessa LM, Martin RW, Matzel T, Maurin D, McNutt SW, Mebus-Antunes NC, Meier BH, Meiser N, Mompeán M, Monaca E, Montserret R, Mariño Perez L, Moser C, Muhle-Goll C, Neves-Martins TC, Ni X, Norton-Baker B, Pierattelli R, Pontoriero L, Pustovalova Y, Ohlenschläger O, Orts J, Da Poian AT, Pyper DJ, Richter C, Riek R, Rienstra CM, Robertson A, Pinheiro AS, Sabbatella R, Salvi N, Saxena K, Schulte L, Schiavina M, Schwalbe H, Silber M, Almeida MDS, Sprague-Piercy MA, Spyroulias GA, Sreeramulu S, Tants JN, Tārs K, Torres F, Töws S, Treviño MÁ, Trucks S, Tsika AC, Varga K, Wang Y, Weber ME, Weigand JE, Wiedemann C, Wirmer-Bartoschek J, Wirtz Martin MA, Zehnder J, Hengesbach M, Schlundt A (2021) Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications. Front Mol Biosci 8: 653148.
47. Vögele J, Ferner JP, Altincekic N, Bains JK, Ceylan B, Fürtig B, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Löhr F, Peter SA, Pyper D, Qureshi NS, Richter C, Schlundt A, Schwalbe H, Stirnal E, Sudakov A, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Duchardt-Ferner E (2021) 1H, 13C, 15N and 31P chemical shift assignment for stem-loop 4 from the 5′-UTR of SARS-CoV-2. Biomol NMR Assign, 15: 335-340.
46. Peter SA, Isaac JS, Narberhaus F, Weigand JE (2021) A novel, universally active C-terminal protein degradation signal generated by alternative splicing. J Mol Biol 433: 166890.
45. Schnieders R, Peter SA, Banijamali E, Riad M, Altincekic N, Bains JK, Ceylan B, Fürtig B, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Oxenfarth A, Petzold K, Qureshi NS, Richter C, Schlagnitweit J, Schlundt A, Schwalbe H, Stirnal E, Sudakov A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J (2021) 1H, 13C and 15N chemical shift assignment of the stem-loop 5a from the 5′-UTR of SARS-CoV-2. Biomol NMR Assign 15: 203-211.
44. Korn SM, Lambertz R, Fürtig B, Hengesbach M, Löhr F, Richter C, Schwalbe H, Weigand JE, Wöhnert J, Schlundt A (2021) 1H, 13C, and 15N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein. Biomol NMR Assign 15: 129-135.
43. Wacker A*, Weigand JE*, Akabayov SR, Altincekic N, Kaur Bains J, Banijamali E, Binas O, Castillo-Martinez J, Cetiner E, Ceylan B, Chiu LY, Davila-Calderon J, Dhamotharan K, Duchardt-Ferner E, Ferner J, Frydman L, Fürtig B, Gallego J, Grün JT, Hacker C, Haddad C, Hähnke M, Hengesbach M, Hiller F, Hohmann KF, Hymon D, de Jesus V, Jonker H, Keller H, Knezic B, Landgraf T, Löhr F, Luo L, Mertinkus KR, Muhs C, Novakovic M, Oxenfarth A, Palomino-Schätzlein M, Petzold K, Peter SA, Pyper DJ, Qureshi NS, Riad M, Richter C, Saxena K, Schamber T, Scherf T, Schlagnitweit J, Schlundt A, Schnieders R, Schwalbe H, Simba-Lahuasi A, Sreeramulu S, Stirnal E, Sudakov A, Tants JN, Tolbert BS, Vögele J, Weiß L, Wirmer-Bartoschek J, Wirtz Martin M, Wöhnert J, Zetzsche H (2020) Breakthrough Article: Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy and DMS footprinting analysis. Nucleic Acids Res 48: 12415-12435. *Erstautor
42. Kubatova N, Qureshi NS, Altincekic N, Abele R, Bains JK, Ceylan B, Ferner J, Fuks C, Hargittay B, Hutchison MT, de Jesus v, Kutz F, Martin MW, Meiser N, Linhardt V, Pyper DJ, Trucks S, Fürtig B, Hengesbach M, Löhr F, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J (2021) 1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10. Biomol NMR Assign 15: 65-71.
41. Schlundt A, Wirtz MA, Knezic B, Hengesbach M, Fürtig B, Weigand JE, Wöhnert J, Ferner J, Saxena K, Wacker A, Richter C, Sreeramulu S, Wirmer-Bartoschek J, Schwalbe H; Im Namen von Mehr als 50 Wissenschaftlerinnen und Wissenschaftlern in Frankfurt und Darmstadt. (2020) Gemeinschaftlich in Krisenzeiten: NMR-Strukturbiologie gegen COVID-19. Biospektrum 26: 440-441.
40. Cantini F, Banci L, Altincekic N, Bains, JK, Dhamotharan K, Fuks C, Fürtig B, Gande SL, Hargittay B, Hengesbach M, Hutchison MT, Korn SM, Kubatova N, Kutz F, Linhard V, Löhr F, Meiser N, Pyper DJ, Qureshi NS, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Tants JN, Wacker A, Weigand JE, Wöhnert J, Tsika AC, Fourkiotis NK, Spyroulias GA (2020) 1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP‑ribose bound forms of the macrodomain of SARS‑CoV‑2 non‑structural protein 3b. Biomol NMR Assign 14: 339-346.
39. Korn SM, Dhamotharan K, Fürtig B, Hengesbach M, Löhr F, Qureshi NS, Richter C, Saxena K, Schwalbe H, Tants JN, Weigand JE, Wöhnert J, Schlundt A (2020) 1H, 13C, and 15N backbone chemical shift assignments of the nucleic acid-binding domain of SARS-CoV-2 non-structural protein 3e. Biomol NMR Assign 14: 329-333.
38. Binas O, Tants JN, Peter SA, Janowski R, Davydova E, Braun J, Niessing D, Schwalbe H, Weigand JE*, Schlundt A* (2020) Structural basis for the recognition of transiently structured AU-rich elements by Roquin. Nucleic Acids Res 48: 7385-7403. *Korrespondenz
37. Fischer S, Di Liddo A, Taylor K, Gerhardus JS, Sobczak K, Zarnack K, Weigand JE (2020) Muscleblind-like 2 controls the hypoxia response of cancer cells. RNA 26: 648-663.
36. Di Liddo A, de Oliveira Freitas Machado C, Fischer S, Ebersberger S, Heumüller AW, Weigand JE, Müller-McNicoll M, Zarnack K (2019) A combined computational pipeline to detect circular RNAs in human cancer cells under hypoxic stress. J Mol Cell Biol 11: 829-844.
35. Gustmann H, Segler AJ, Gophane DB, Reuss AJ, Grünewald C, Braun M, Weigand JE, Sigurdsson ST, Wachtveitl J (2019) Structure guided fluorescence labeling reveals a two-step binding mechanism of neomycin to its RNA aptamer. Nucleic Acids Res 47: 15-28.
34. Hetzke T, Vogel M, Gophane DB, Weigand JE, Suess B, Sigurdsson ST, Prisner TF (2019) Influence of Mg2+ on the conformational flexibility of a tetracycline aptamer. RNA 25: 158-167.
33. Braun J, Fischer S, Xu ZZ, Sun H, Ghoneim DH, Gimbel AT, Plessman U, Urlaub H, Mathews DH, Weigand JE (2018) Identification of new high affinity targets for Roquin based on structural conservation. Nucleic Acids Res 46: 12109-12125.
32. Vogel M, Weigand JE, Kluge B, Grez M, Suess B (2018) A small, portable RNA device for the control of exon skipping in mammalian cells. Nucleic Acids Res 46: e48.
31. Suess B, Weigand JE, Kemmerer K (2018) Splicing and Alternative Splicing – Impact on gene design. In Wiley-Blackwell: Synthetic Biology – Parts, Devices and Applications, Volume 8: 131-179.
30. Kemmerer K, Fischer S, Weigand JE (2018) Auto- and cross-regulation of the hnRNPs D and DL. RNA 24: 324-331.
29. Atanasov J, Groher F, Weigand JE*, Suess B* (2017) Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals. Nucleic Acids Res 45: e181. *Korrespondenz
28. Kunze MM, Benz F, Brauß TF, Lampe S, Weigand JE, Braun J, Richter FM, Wittig I, Brüne B, Schmid T (2016) sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism. Biochim Biophys Acta 1859: 848-859.
27. Duchardt-Ferner E, Gottstein-Schmidtke SR, Weigand JE, Ohlenschläger O, Wurm JP, Hammann C, Suess B, Wöhnert J (2016) What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch. Angew Chem Int Ed Engl 55: 1527-1530.
26. Rohde JH, Weigand JE, Suess B, Dimmeler S (2015) A universal aptamer chimera for the delivery of functional microRNA-126. Nucleic Acid Ther 25: 141-151.
25. Reuss AJ, Vogel M, Weigand JE, Suess B, Wachtveitl J (2014) Tetracycline Determines the Conformation of its Aptamer at Physiological Magnesium Concentrations. Biophys J 107: 2962-2971.
24. Kemmerer K, Weigand JE (2014) Hypoxia reduces MAX expression in endothelial cells by unproductive splicing. FEBS Lett 588: 4784-4790.
23. Weigand JE, Gottstein-Schmidtke SR, Demolli S, Groher F, Duchardt-Ferner E, Wöhnert J, Suess B (2014) VIP Article: Sequence elements distal to the ligand binding pocket modulate the efficiency of a synthetic riboswitch. Chembiochem 15: 1627-1637.
22. Gottstein-Schmidtke SR, Duchardt-Ferner E, Groher F, Weigand JE, Gottstein D, Suess B, Wöhnert J (2014) Building a stable RNA U-turn with a protonated cytidine. RNA 20: 1163-1172.
21. Demolli S, Geist MM, Weigand JE, Matschiavelli N, Suess B, Rother M (2014) Development of beta-Lactamase as a Tool for Monitoring Conditional Gene Expression by a Tetracycline-Riboswitch in Methanosarcina acetivorans. Archaea 2014: 725610.
20. Meitert J, Aram R, Wiesemann K, Weigand JE, Suess B (2013) Monitoring the expression level of coding and non-coding RNAs using a TetR inducing aptamer tag. Bioorg Med Chem 21: 6233-6238.
19. Heinrich EM, Wagner J, Krüger M, John D, Uchida S, Weigand JE, Suess B, Dimmeler S (2013) Regulation of miR-17-92a cluster processing by the microRNA binding protein SND1. FEBS Lett 587: 2405-2411.
18. Weigand JE*, Boeckel JN, Gellert P, Dimmeler S (2012) Hypoxia-induced alternative splicing in endothelial cells. PLoS One7: e42697. *Korrespondenz
17. Suess B, Entian KD, Kötter P, Weigand JE (2012) Aptamer-regulated expression of essential genes in yeast. Methods Mol Biol824: 381-391.
16. Weigand JE, Wittmann A, Suess B (2012) RNA-based networks: using RNA aptamers and ribozymes as synthetic genetic devices. Methods Mol Biol 813: 157-168.
15. Förster U, Weigand JE, Trojanowski P, Suess B, Wachtveitl J (2012) Conformational dynamics of the tetracycline-binding aptamer. Nucleic Acids Res 40: 1807-1817.
14. Weigand JE, Schmidtke SR, Will TJ, Duchardt-Ferner E, Hammann C, Wöhnert J, Suess B (2011) Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity. Nucleic Acids Res 39: 3363-3372.
13. Wunnicke D, Strohbach D, Weigand JE, Appel B, Feresin E, Suess B, Müller S, Steinhoff HJ (2011) Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR. RNA 17: 182-188.
12. Duchardt-Ferner E, Weigand JE, Ohlenschläger O, Schmidtke SR, Suess B, Wöhnert J (2010) Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. Angew Chem Int Ed Engl 49: 6216-6219.
11. Nozinovic S, Richter C, Rinnenthal J, Fürtig B, Duchardt-Ferner E, Weigand JE, Schwalbe H (2010) Quantitative 2D and 3D Gamma-HCP Experiments for the Determination of the Angles alpha and zeta in the Phosphodiester Backbone of Oligonucleotides. J Am Chem Soc 132: 10318-10329.
10. Schmidtke SR, Duchardt-Ferner E, Weigand JE, Suess B, Wöhnert J (2010) NMR resonance assignments of an engineered neomycin-sensing riboswitch RNA bound to ribostamycin and tobramycin. Biomol NMR Assign 4: 115-118.
9. Krstic I, Frolow O, Sezer D, Endeward B, Weigand JE, Suess B, Engels JW, Prisner TF (2010) PELDOR spectroscopy reveals preorganization of the neomycin-responsive riboswitch tertiary structure. J Am Chem Soc 132: 1454-1455.
8. Weigand JE, Suess B (2009) Aptamers and riboswitches: perspectives in biotechnology. Appl Microbiol Biotechnol 85: 229-236.
7. Kötter P, Weigand JE, Meyer B, Entian KD, Suess B (2009) A fast and efficient translational control system for conditional expression of yeast genes. Nucleic Acids Res 37: e120.
6. Suess B, Weigand JE (2009) Aptamers as artificial gene regulation elements. Methods Mol Biol535: 201-208.
5. Suess B, Weigand JE (2008) Engineered riboswitches: overview, problems and trends. RNA Biol 5: 24-29.
4. Weigand JE, Sanchez M, Gunnesch EB, Zeiher S, Schroeder R, Suess B (2008) Screening for engineered neomycin riboswitches that control translation initiation. RNA 14: 89-97.
3. Weigand JE, Suess B (2007) Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast. Nucleic Acids Res 35: 4179-4185.
2. Weigand JE, Suess B (2007) A designed RNA shuts down transcription. Chem Biol 14: 9-11.
1. Müller M, Weigand JE, Weichenrieder O, Suess B (2006) Thermodynamic characterization of an engineered tetracycline-binding riboswitch. Nucleic Acids Res 34: 2607-2617.
