Publications

Publications in PubMed here

35.   Gustmann H, Segler AJ, Gophane DB, Reuss AJ, Grünewald C, Braun M, Weigand JE, Sigurdsson ST, Wachtveitl J (2019) Structure guided fluorescence labeling reveals a two-step binding mechanism of neomycin to its RNA aptamer. Nucleic Acids Res 47: 15-28.

34.   Hetzke T, Vogel M, Gophane DB, Weigand JE, Suess B, Sigurdsson ST, Prisner TF (2019) Influence of Mg2+ on the conformational flexibility of a tetracycline aptamer. RNA 25: 158-167.

33.   Braun J, Fischer S, Xu ZZ, Sun H, Ghoneim DH, Gimbel AT, Plessman U, Urlaub H, Mathews DH, Weigand JE (2018) Identification of new high affinity targets for Roquin based on structural conservation. Nucleic Acids Res 46: 12109-12125.

32.   Vogel M, Weigand JE, Kluge B, Grez M, Suess B (2018) A small, portable RNA device for the control of exon skipping in mammalian cells. Nucleic Acids Res 46: e48.

31.   Suess B, Weigand JE, Kemmerer K (2018) Splicing and Alternative Splicing – Impact on genedesign. In Wiley-Blackwell: SyntheticBiology – Parts, Devices and Applications, Volume 8: 131-179.

30.   Kemmerer K, Fischer S, Weigand JE (2018) Auto- and cross-regulation of the hnRNPs D and DL. RNA 24: 324-331.

29.   Atanasov J, Groher F, Weigand JE, Suess B (2017) Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals. Nucleic Acids Res 45: e181.

28.   Kunze MM, Benz F, Brauß TF, Lampe S, Weigand JE, Braun J, Richter FM, Wittig I, Brüne B, Schmid T (2016) sST2 translation is regulated by FGF2 via an hnRNP A1-mediated IRES-dependent mechanism. Biochim Biophys Acta 1859: 848-859.

27.   Duchardt-Ferner E, Gottstein-Schmidtke SR, Weigand JE, Ohlenschläger O, Wurm JP, Hammann C, Suess B, Wöhnert J (2016) What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch. Angew Chem Int Ed Engl 55: 1527-1530.

26.   Rohde JH, Weigand JE, Suess B, Dimmeler S (2015) A universal aptamer chimera for the delivery of functional microRNA-126. Nucleic Acid Ther 25: 141-151.

25.   Reuss AJ, Vogel M, Weigand JE, Suess B, Wachtveitl J (2014) Tetracycline Determines the Conformation of its Aptamer at Physiological Magnesium Concentrations. Biophys J 107: 2962-2971.

24.   Kemmerer K, Weigand JE (2014) Hypoxia reduces MAX expression in endothelial cells by unproductive splicing. FEBS Lett 588: 4784-4790.

23.   Weigand JE, Gottstein-Schmidtke SR, Demolli S, Groher F, Duchardt-Ferner E, Wöhnert J, Suess B (2014) Sequence elements distal to the ligand binding pocket modulate the efficiency of a synthetic riboswitch. Chembiochem 15: 1627-1637.

22.   Gottstein-Schmidtke SR, Duchardt-Ferner E, Groher F, Weigand JE, Gottstein D, Suess B, Wöhnert J (2014) Building a stable RNA U-turn with a protonated cytidine. RNA 20: 1163-1172.

21.   Demolli S, Geist MM, Weigand JE, Matschiavelli N, Suess B, Rother M (2014) Development of beta-Lactamase as a Tool for Monitoring Conditional Gene Expression by a Tetracycline-Riboswitch in Methanosarcina acetivorans. Archaea 2014: 725610.

20.   Meitert J, Aram R, Wiesemann K, Weigand JE, Suess B (2013) Monitoring the expression level of coding and non-coding RNAs using a TetR inducing aptamer tag. Bioorg Med Chem 21: 6233-6238.

19.   Heinrich EM, Wagner J, Krüger M, John D, Uchida S, Weigand JE, Suess B, Dimmeler S (2013) Regulation of miR-17-92a cluster processing by the microRNA binding protein SND1. FEBS Lett 587: 2405-2411.

18.   Weigand JE, Boeckel JN, Gellert P, Dimmeler S (2012) Hypoxia-induced alternative splicing in endothelial cells.PLoS One7: e42697.

17.   Suess B, Entian KD, Kötter P, Weigand JE(2012) Aptamer-regulated expression of essential genes in yeast. Methods Mol Biol824: 381-391.

16.   Weigand JE, Wittmann A, Suess B (2012) RNA-based networks: using RNA aptamers and ribozymes as synthetic genetic devices. Methods Mol Biol 813: 157-168.

15.   Förster U, Weigand JE, Trojanowski P, Suess B, Wachtveitl J (2012) Conformational dynamics of the tetracycline-binding aptamer. Nucleic Acids Res 40: 1807-1817.

14.   Weigand JE, Schmidtke SR, Will TJ, Duchardt-Ferner E, Hammann C, Wöhnert J, Suess B (2011) Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity. Nucleic Acids Res 39: 3363-3372.

13.   Wunnicke D, Strohbach D, Weigand JE, Appel B, Feresin E, Suess B, Müller S, Steinhoff HJ (2011) Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR. RNA 17: 182-188.

12.   Duchardt-Ferner E, Weigand JE, Ohlenschläger O, Schmidtke SR, Suess B, Wöhnert J (2010) Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. Angew Chem Int Ed Engl 49: 6216-6219.

11.   Nozinovic S, Richter C, Rinnenthal J, Fürtig B, Duchardt-Ferner E, Weigand JE, Schwalbe H (2010) Quantitative 2D and 3D Gamma-HCP Experiments for the Determination of the Angles alpha and zeta in the Phosphodiester Backbone of Oligonucleotides. J Am Chem Soc 132: 10318-10329.

10.   Schmidtke SR, Duchardt-Ferner E, Weigand JE, Suess B, Wöhnert J (2010) NMR resonance assignments of an engineered neomycin-sensing riboswitch RNA bound to ribostamycin and tobramycin. Biomol NMR Assign 4: 115-118.

9. Krstic I, Frolow O, Sezer D, Endeward B, Weigand JE, Suess B, Engels JW, Prisner TF (2010) PELDOR spectroscopy reveals preorganization of the neomycin-responsive riboswitch tertiary structure. J Am Chem Soc 132: 1454-1455.

8.   Weigand JE, Suess B (2009) Aptamers and riboswitches: perspectives in biotechnology. Appl Microbiol Biotechnol 85: 229-236.

7.   Kötter P, Weigand JE, Meyer B, Entian KD, Suess B (2009) A fast and efficient translational control system for conditional expression of yeast genes. Nucleic Acids Res 37: e120.

6.   Suess B, Weigand JE (2009) Aptamers as artificial gene regulation elements. Methods Mol Biol535: 201-208.

5.   Suess B, Weigand JE (2008) Engineered riboswitches: overview, problems and trends. RNA Biol 5: 24-29.

4.   Weigand JE, Sanchez M, Gunnesch EB, Zeiher S, Schroeder R, Suess B (2008) Screening for engineered neomycin riboswitches that control translation initiation. RNA 14: 89-97.

3.   Weigand JE, Suess B (2007) Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast. Nucleic Acids Res 35: 4179-4185.

2.   Weigand JE, Suess B (2007) A designed RNA shuts down transcription. Chem Biol 14: 9-11.

1.   Müller M, Weigand JE, Weichenrieder O, Suess B (2006) Thermodynamic characterization of an engineered tetracycline-binding riboswitch. Nucleic Acids Res 34: 2607-2617.